Generally it was seen that people recovered completely from Covid-19 infection in 15 to 30 days. Many such cases were also seen in which it took 100 or more days for the patient to become infection free. Nevertheless, there were some cases in which the virus remained in the patients for hundreds of days. The most shocking case among these is that of a 72-year-old man from Holland, who was infected for 613 days before dying.
According to scientists, the virus mutated about 50 times during this period. They warn that people with weakened immune systems, like this man, are ideal incubators for deadly new strains of the disease. The 72-year-old man is believed to have had the longest-lasting infection.
Healthy patients usually clear the virus within a few days to weeks, but people with weakened immunity may develop persistent infection with prolonged viral replication and growth. Scientists believe that the Omicron variant, which emerged in late 2021, originated in an immunocompromised individual, highlighting the need for vigilant monitoring of such patients.
In February 2022, an elderly man was admitted to the Amsterdam University Medical Center suffering from a Covid infection, believed to be the Omicron variant. The patient had a history of stem cell transplant treatment, which classified him as immunocompromised. His condition was further complicated by the development of post-transplant lymphoma, for which he was receiving a targeted cancer drug that destroys all available B-cells, including the cells responsible for producing Covid antibodies. Are.
However, researchers discovered that the virus had developed resistance mutations to sotrovimab just 21 days after receiving the antibodies. They also saw minimal anti-spike antibody development in the first month, suggesting that the patient’s immune system was unable to eliminate the virus. Ultimately that elderly man died due to the recurrence of some disease present in his blood. According to researchers, he remained Covid positive with high viral load for a total of 613 days.
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FIRST PUBLISHED: April 19, 2024, 11:22 IST